Ultrafast and absolute quantification of SARS-CoV-2 on food using hydrogel RT-LAMP without pre-lysisArticle Published on 2023-01-152022-11-16 Journal: Journal of hazardous materials [Category] SARS, 치료기술, [키워드] Absolute quantification acute respiratory syndrome amplification cold chain Cold chain food contact infection coronavirus faster Food industry hydrogel Hydrogel RT-LAMP isothermal amplification microbe offer POCT point-of-care quantification reproducibility reverse transcription RNA RNA extraction RT-LAMP SARS-CoV-2 sensitivity specificity stability Surveillance Ultrafast detection. virus [DOI] 10.1016/j.jhazmat.2022.130050 PMC 바로가기
Synthesis of new Spiropyrazole derivatives under microwaves irradiation and docking study for inhibition the microbes and COVID-19Research article Published on 2022-12-012022-10-05 Journal: Journal of Molecular Structure [Category] 치료제, [키워드] 6LU7 addition analysis antimicrobial Antiviral binding Candida albican Complete Complexes COVID-19 derivative derivatives docking docking score docking study domain Effectiveness Hydrazonoyl halides indicated inhibit Interaction Laboratory microbe microwave Microwaves physicochemical property protease Seven Spiropyrazoles synthesis tested these compound with COVID-19 [DOI] 10.1016/j.molstruc.2022.133581 [Article Type] Research article
A computational approach to biological pathogenicityArticle Published on 2022-11-012022-11-15 Journal: Molecular genetics and genomics : MGG [Category] 바이오마커, [키워드] Accuracy adverse impact approach assessment Biochemistry Biomarkers clinical trial COVID-19 death Digital Digital genomic signature DNA DNA sequence energy event feature genomic Gibbs energy h-distance. Health Host humans hybridization machine machine learning machine learning model methodology microbe mitigate new strain oligonucleotide Other pandemic pathogen pathogenic Pathogenic relationship pathogenicity Pathogens/nonpathogens Perspective predict Quality reducing sensitivity Sensitivity and specificity Sickness specificity structural property [DOI] 10.1007/s00438-022-01951-w PMC 바로가기
Methicillin-resistant staphylococcus aureus nosocomial infection has a distinct epidemiological position and acts as a marker for overall hospital-acquired infection trendsArticle Published on 2022-10-112022-11-15 Journal: Scientific Reports [Category] 바이오마커, [키워드] Analysis Biomarker Care Control COVID-19 pandemic dataset disease Diseases drug-resistant Efficacy epidemiological epidemiologist HAI healthcare hospital hospitalized patients Infection lack Lower marker microbe MRSA Nosocomial infection Nosocomial infections outbreak pathogen Patient prevented reduced replaced Staphylococcus aureus Stress threshold unique USA [DOI] 10.1038/s41598-022-21300-6 PMC 바로가기
Aseptic Abscess Syndrome in Rheumatoid Arthritis PatientArticle Published on 2022-09-272022-11-15 Journal: Medicina [Category] 진단, [키워드] abdominal pain abscess accompanied adalimumab Antibiotics Aseptic aseptic abscess syndrome Autoimmune diseases Bacteria characterized Clinical improvement Complete corticosteroid therapy COVID-19 infection disorder extension feature Fever IBD include Inflammatory Inflammatory bowel disease Inflammatory marker internal organ joints lack lesion lesions Leukocytosis liver Lungs microbe neutrophilic parasites Patient potentially life-threatening Practitioner Prednisone recognize reduction Remdesivir Rheumatoid rheumatoid arthritis rheumatoid arthritis. sensitivity spleen Symptom syndrome systemic symptom tissue treated Treatment viruses weight loss [DOI] 10.3390/medicina58101354 PMC 바로가기
Dynamic Alterations in the Respiratory Tract Microbiota of Patients with COVID-19 and its Association with Microbiota in the GutArticle Published on 2022-09-012022-11-15 Journal: Advanced Science [Category] 바이오마커, [키워드] Actinomyces alteration analyzed Bacteroide Biomarker Candida contributing to coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 progression determine Diagnosis disease Disease progression disease severity dynamic Enterococcus Fecal sample Gut gut microbiota ICU ICU Patients identify immune response Increases intensive care intensive care unit metagenome microbe microbial Microbiome microbiota mononuclear cell non-ICU pathway Patient patients patients with COVID-19 PBMC Peripheral blood positive correlation reduced respiratory respiratory microbiota. respiratory tract sequenced Significant significantly sputum Stage Streptococcus tract Treatment strategies with COVID-19 [DOI] 10.1002/advs.202200956 PMC 바로가기
Chapter 12: Insight into coronaviruses and natural products-based approach for COVID-19 treatmentBook chapter Published on 2022-07-192022-10-05 Journal: Molecules [Category] 신약개발, 치료법, [키워드] Analysis Anticoronaviral natural products approach caused Contagion coronavirus coronavirus Coronaviruses COVID-19 Defense disease drug effective humans include insight metabolite microbe molecular docking natural nontoxic pandemic of COVID-19 Pathogens performed plant Safe SARS-CoV-2 Secondary Metabolite shown Side effect specificity therapeutic targets Treatment [DOI] 10.1016/B978-0-323-91099-6.00005-0 [Article Type] Book chapter
Hypoxia signaling in human health and diseases: implications and prospects for therapeutics Reviews Published on 2022-07-072022-10-05 Journal: Signal Transduction and Targeted Therapy [Category] 신약개발, [키워드] Activation addition biological processes Cancer Cell cell metabolism cell proliferation cellular pathways change Chronic diseases disease Diseases downstream gene drugs Endoplasmic reticulum ERK expression Extracellular Factor Glycolysis Health hypoxia immune response implication Infection interact involved kinase mammalian cells mechanism Metastasis microbe Molecular oxygen NF-κB nuclear oxygen pathogenic pathway question Rapamycin reaction regulate respond responses Signaling Stress subsequent therapeutic therapeutic target tumorigenesis [DOI] 10.1038/s41392-022-01080-1 [Article Type] Reviews
Microbial Natural Products with Antiviral Activities, Including Anti-SARS-CoV-2: A ReviewAnti-SARS-CoV-2를 포함한 항바이러스 활성이 있는 미생물 천연 제품: 검토Review Published on 2022-07-052022-09-11 Journal: Molecules [Category] COVID19(2023년), SARS, 신약개발, 유전자 메커니즘, 치료제, [키워드] anti-SARS-CoV-2 Anti-SARS-CoV-2 Activity antiviral activity antiviral drug antiviral drugs aspulvinone aurasperone Bacterial caused Compound COVID-19 COVID-19 infection death described develop disease drug Drug discovery Evidence fungal global pandemic in vitro in vivo Including increase in Infection M pro mechanism mechanism of action microbe microbes microorganism microorganisms natural natural products. penicillin produced product protease recent Research resulting review SARS-CoV-2 SARS-CoV-2 virus shown simplex Spread these compound these compounds treat Vaccine viral infections virus [DOI] 10.3390/molecules27134305 PMC 바로가기 [Article Type] Review
A kiosk survey of perception, attitudes and knowledge (PAK) of Australians concerning microbes, antibiotics, probiotics and hygieneArticle Published on 2022-07-012022-11-16 Journal: Health promotion journal of Australia : official j [Category] COVID19(2023년), SARS, 치료기술, [키워드] addition age analysed analysis antibiotic Antibiotics approaches Aspirin Australian Australians baseline comparison concerning FIVE Gender history hygiene Infectious disease Interaction issue knowledge lack microbe microbes misunderstanding natural pandemic question Seven Spread stimulate while [DOI] 10.1002/hpja.530 PMC 바로가기